Proteomics Research
Understanding protein structure, function, and interactions to unlock new therapeutic possibilities. Our proteomics program combines structural biology, mass spectrometry, and enzyme engineering to push the boundaries of molecular discovery.
Structural Biology
Using cryo-electron microscopy and X-ray crystallography to determine protein structures at atomic resolution. These structural insights guide drug design and reveal molecular mechanisms underlying biological processes.
Protein Characterization
Comprehensive protein analysis using advanced mass spectrometry, chromatography, and spectroscopy techniques. We characterize post-translational modifications, protein-protein interactions, and conformational dynamics.
Enzyme Engineering
Designing and optimizing enzymes for industrial, therapeutic, and research applications. We use directed evolution and rational design to create enzymes with enhanced activity, stability, and specificity.
Mass Spectrometry
Our proteomics facility operates state-of-the-art mass spectrometers for quantitative proteomics, biomarker discovery, and metabolomics. High-throughput workflows enable large-scale protein profiling studies.
Key Projects
Structural Proteomics Initiative
Systematic determination of protein structures involved in disease pathways. This initiative generates high-resolution structures to accelerate structure-based drug design for challenging therapeutic targets.
Enzyme Engineering Lab
Developing engineered enzymes for pharmaceutical synthesis, industrial biocatalysis, and environmental remediation. Our lab combines directed evolution with computational protein design to create bespoke biocatalysts.
Diagnostic Biomarker Discovery
Identifying and validating protein biomarkers for early disease detection and monitoring. Using proteomics-based discovery pipelines to develop diagnostic assays with clinical-grade sensitivity and specificity.
Leadership Team
Dr. Elena Rodriguez
Director, Proteomics Research
Pioneering structural proteomics approaches with a focus on membrane protein complexes and their roles in neurodegenerative diseases.
Dr. James Park
Senior Scientist, Proteomics
Specialist in enzyme engineering and directed evolution, with extensive experience in developing industrial biocatalysts for pharmaceutical manufacturing.
Collaborate With Us
Seeking access to our structural biology or mass spectrometry facilities? We partner with academic and industry groups to advance proteomics research and develop novel applications.
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